Vitamin D Science
Lipid matrices for vitamin D3: absorption pathways compared
The popular claim is simple: vitamin D3 is fat-soluble, therefore adding it to a fatty food automatically solves the absorption problem. The serum…
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Vitamin D Science
Explore peer-reviewed data, policy briefs, and clinical trials categorized by key themes in micronutrient science and public health.
Vitamin D Science
Baseline serum vitamin D assessment: essential pre-trial steps
Every vitamin D clinical trial begins with the same convenient assumption: that the serum values streaming off hospital immunoassay analyzers are…
Vitamin D Science
Clinical trial protocols for vitamin D: essential pre-study data
The supplement industry’s favorite shortcut is to treat vitamin D as a universal intervention and then interpret a weak trial as a verdict on the…
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New Evidence Links Vitamin D Supplementation to Better Clinical Outcomes in IBD Patients
Pop a daily multivitamin, soak up some sun, and move on — that is the wellness industry's tidy script for inflammatory bowel disease, and according…
Vitamin D Science
Serum 25-hydroxyvitamin D variability in clinical trials
Every clinical trial on vitamin D begins with a measurement. Most of them end with a measurement too — and a confident claim that supplementation…
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Does Personalized Vitamin D Titration Improve Outcomes After a Heart Attack?
The TARGET-D trial, now indexed in the European Heart Journal, finally drags that slogan into a randomized design and asks the only question that…
News
Can High-Dose Vitamin D Supplements Actually Boost Cognitive Performance?
According to Technology Networks, an Emory University study is being framed as proof that high-dose vitamin D improves cognition in older adults with…
Vitamin D Science
Bone Health Endpoints: DXA or Turnover Markers for Your Trial?
In osteoporosis trials, the choice between DXA and bone turnover markers is not a contest between an old technology and a newer one. It is a decision…
News
Vitamin D Supplementation and Metabolic Health: A Review of Clinical Evidence
A new systematic review in Nutrire covering 11 studies suggests that vitamin D supplementation may modestly improve glycemic control, insulin…
Vitamin D Science
Calcium absorption assays: matching the method to your trial
A calcium absorption study can look technically sophisticated and still answer the wrong question. The central design choice is not simply whether a…
News
Low Vitamin D Levels Linked to Increased Risk of Retinal Vein Occlusion
According to a propensity-score-matched cohort study published in Scientific Reports, adults aged 50 and older with serum 25-hydroxyvitamin D below…
Vitamin D Science
BMD clinical trials: DXA calibration pitfalls
A bone mineral density trial can lose analytical validity before the first biological endpoint is analyzed. The failure point is often not the…
Vitamin D Science
VDR gene polymorphisms: when to stratify clinical trial cohorts
The nutritional supplement industry loves a simple narrative. Take more cholecalciferol, raise your serum 25(OH)D, fix your deficiency, harden your…
News
Vitamin D Deficiency in Intensive Care: Analyzing Clinical Outcome Correlations
The PubMed-listed retrospective cohort study reports that critically ill patients with vitamin D deficiency had worse clinical outcomes.
Vitamin D Science
Serum 25(OH)D assays: avoiding costly trial errors
Clinical vitamin D trials can fail at the measurement stage before any biological conclusion is reached. The problem is not limited to an incorrect…
Vitamin D Science
Does vitamin D prevent acute respiratory infections?
The wellness industry will tell you that vitamin D is an immune booster. Population-level clinical biochemistry disagrees, and the disagreement is…
Vitamin D Science
Vitamin D forms: which chemical path suits your trial?
In vitamin D research, the choice between cholecalciferol and calcifediol is not a minor formulation detail. It determines how much of the metabolic…
News
Can Vitamin D Supplements Help Manage Rheumatoid Arthritis Symptoms?
PubMed reports that a 90-day course of vitamin D and calcium supplementation in patients with active rheumatoid arthritis was associated with…
Vitamin D Science
Does magnesium deficiency block your vitamin D?
Here is the nutritional industry's favorite script: take 5,000 IU of cholecalciferol, watch serum 25-hydroxyvitamin D climb, mission accomplished…
Vitamin D Science
Calcium absorption kinetics: which pathway suits your patient?
When vitamin D status is poor, the intestine may absorb only 10–15% of the calcium presented in food. Across more typical conditions, free-living…
Vitamin D Science
Cholecalciferol bioavailability: errors that waste study time
A cholecalciferol bioavailability trial can fail before the first dose is administered. The most common failure is not poor capsule manufacture or…
Vitamin D Science
Vitamin D receptor saturation: do mega-doses work?
Walk into any pharmacy and you will find the same pitch on the shelf: a single 50,000 IU or even 100,000 IU vitamin D capsule marketed as a…
Vitamin D Science
Vitamin D pathways: which absorption route suits you?
Vitamin D deficiency is often treated as if the main question were simply how many international units a person receives. That approach overlooks the…